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AADC deficiency (AADCD; OMIM 608643) is a rare, autosomal recessive neurometabolic disorder that leads to a severe combined deficiency of serotonin, dopamine, norepinephrine and epinephrine (Fig. 1) [1].

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Dendritic cell-associated B7-H3 suppresses the production of autoantibodies and renal inflammation in a mouse model of systemic lupus erythematosus – Interestingly, immunization of mice with DNA-pulsed dendritic cells induced severe sle symptoms while B7-H3 on dendritic cells. To test this, anti-CD4 mAb GK1.5 was injected into mice repeatedly to.

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